| Identification | Back Directory | [Name]
1-β-D-Arabinofuranosyl-5-iodo-2,4(1H,3H)-pyrimidinedione | [CAS]
3052-06-0 | [Synonyms]
NSC 82221
5-Iodoarabinouridine
1-β-D-Arabinofuranosyl-5-iodouracil
1-β-D-Arabinofuranosyl-5-iodo-2,4(1H,3H)-pyrimidinedione
2,4(1H,3H)-Pyrimidinedione, 1-β-D-arabinofuranosyl-5-iodo-
5-Iodoarabinouridine, 1-(β-D-arabino-furanosyl)-5-iodouracil
1-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-iodo-pyrimidine-2,4-dione | [Molecular Formula]
C9H11IN2O6 | [MDL Number]
MFCD00672162 | [MOL File]
3052-06-0.mol | [Molecular Weight]
370.1 |
| Hazard Information | Back Directory | [Uses]
1-Beta-D-arabinofuranosyl-5-iodouracil is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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