| Identification | Back Directory | [Name]
Benzamide, N-[3-(1H-benzimidazol-2-yl)phenyl]-3-methyl- | [CAS]
305357-89-5 | [Synonyms]
WAY-304388
CHEMBL1276927
Benzamide, N-[3-(1H-benzimidazol-2-yl)phenyl]-3-methyl-
N-(3-(1H-Benzo[d]imidazol-2-yl)phenyl)-3-methylbenzamide | [Molecular Formula]
C21H17N3O | [MOL File]
305357-89-5.mol | [Molecular Weight]
327.38 |
| Chemical Properties | Back Directory | [Melting point ]
220-221 °C(Solv: acetonitrile (75-05-8)) | [density ]
1.281±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
11.33±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
GLUT1-IN-2 (compound 17) is a GLUT1 inhibitor with an IC50 value of 12 μM. GLUT1-IN-2 shows inhibitory effect to Plasmodium falciparum hexose transporter PfHT with an IC50 value of 13 μM. GLUT1-IN-2 can be used for the research of infection[1]. | [References]
[1] Ortiz D, et al. Identification of Selective Inhibitors of the Plasmodium falciparum Hexose Transporter PfHT by Screening Focused Libraries of Anti-Malarial Compounds. PLoS One. 2015 Apr 20;10(4):e0123598. DOI:10.1371/journal.pone.0123598 |
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