| Identification | Back Directory | [Name]
N'-benzylpivalohydrazide | [CAS]
306-19-4 | [Synonyms]
Angorvit
Ro 4-1634
Betamezid
Betamezide
Brn 0744565
Einecs 206-180-9
pivalylbenzhydrazine
N-Benzyl pivalhydrazide
N'-benzylpivalohydrazide
2971-75-7 (Hydrochloride)
Pivalic acid, 2-benzylhydrazide
N'-benzyl-2,2-dimethylpropanehydrazide
2,2-Dimethylpropanoic acid 2-(phenylmethyl)hydrazide
2,2-Dimethyl-N'-(phenylmethyl)propanoic acid hydrazide | [EINECS(EC#)]
206-180-9 | [Molecular Formula]
C12H18N2O | [MDL Number]
MFCD00449118 | [MOL File]
306-19-4.mol | [Molecular Weight]
206.284 |
| Safety Data | Back Directory | [RIDADR ]
3249 | [HazardClass ]
6.1(b) | [PackingGroup ]
III | [Toxicity]
mouse,LD50,intravenous,> 280mg/kg (280mg/kg),Psychopharmacology Service Center, Bulletin. Vol. 2, Pg. 17, 1963. |
| Hazard Information | Back Directory | [Uses]
Pivalylbenzhydrazine (Pivhydrazine) is a potent monoamine oxidase (MAO) inhibitor. Pivalylbenzhydrazine decreases cartilage growth in normal rats. Pivalylbenzhydrazine can be used in research of depression[1]. | [Definition]
ChEBI: Pivhydrazine is a member of benzenes. | [in vivo]
Pivalylbenzhydrazine (Pivhydrazine; 5 mg/kg; i.p.; daily, for 5 d; immature female rats) inhibits the growth of the epiphysial cartilage[1]. | Animal Model: | Immature female rats (40 g, 3-4 weeks age)[1] | | Dosage: | 5 mg/kg | | Administration: | Intraperitoneal injection; daily, for 5 days | | Result: | Inhibited the growth of the epiphysial cartilage |
| [References]
[1] Zor U, et, al. The effect of monoamine oxidase inhibitors on growth and the rat tibia test. J Endocrinol. 1965 Apr;32:35-43. DOI:10.1677/joe.0.0320035 |
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