| Identification | Back Directory | [Name]
N-Phenylquinoline-4-amine | [CAS]
30696-07-2 | [Synonyms]
4-Anilinoquinoline
n-phenylquinolin-4-aMine
N-Phenylquinoline-4-amine
phenyl-quinolin-4-yl-amine
4-Quinolinamine, N-phenyl- | [Molecular Formula]
C15H12N2 | [MDL Number]
MFCD00958207 | [MOL File]
30696-07-2.mol | [Molecular Weight]
220.27 |
| Hazard Information | Back Directory | [Synthesis]
N-phenylquinolin-4-amine was prepared by adding aniline to 4-chloroquinoline ethanol solution under microwave irradiation at 165°C.To a solution of 4-chloroquinoline (350 mg, 2.14 mmol) in ethanol (3 ml), aniline (996 mg, 10.7 mmol) was added and the mixture was reacted at 165 °C for 3 hours under microwave radiation. The reaction mixture was concentrated in vacuo, aqueous sodium carbonate (25 ml) was added and this was then extracted using dichloromethane (3×30 ml). The organic extracts were collected, dried using magnesium sulphate, concentrated in vacuo and the resulting residue was purified by flash column chromatography eluting with 2% methanol in dichloromethane to give the title compound as a colourless solid (42 mg, 9%). |
|
| Company Name: |
Matrix Scientific
|
| Tel: |
803 788-9494 All other calls |
| Website: |
www.matrixscientific.com |
|