| Identification | Back Directory | [Name]
isocolchicine | [CAS]
30771-10-9 | [Synonyms]
isocolchicine
(7S)-Isocolchicine
(S)-7α-Acetylamino-6,7-dihydro-1,2,3,9-tetramethoxybenzo[a]heptalen-10(5H)-one
Acetamide, N-(5,6,7,10-tetrahydro-1,2,3,9-tetramethoxy-10-oxobenzo(A)heptalen-7-yl)-
N-[(7S)-5,6,7,10-Tetrahydro-1,2,3,9-tetraMethoxy-10-oxobenzo[a]heptalen-7-yl]acetaMide
(7S)-1,2,3,9-Tetramethoxy-7α-(acetylamino)-5,6,7,10-tetrahydrobenzo[a]heptalene-10-one | [Molecular Formula]
C22H25NO6 | [MOL File]
30771-10-9.mol | [Molecular Weight]
399.44 |
| Chemical Properties | Back Directory | [Melting point ]
226°C | [Boiling point ]
726.031±60.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.256±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [pka]
14.509±0.40(predicted) |
| Hazard Information | Back Directory | [Description]
This minor alkaloid occurs in the corms and seeds of Colchicum autumnale,
Gloriosa virescens and Littoria modesta. It is laevorotatory having a specific
rotation of [α]D - 307° (CHCI3). It may be separated from the numerous
accompanying bases by column and thin layer chromatography. | [References]
Potesilova, Hrbek, Santavy, Collect. Czech. Chem. Commun., 32, 141 (1967) |
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