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308356-20-9

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308356-20-9 Structure

308356-20-9 Structure
IdentificationBack Directory
[Name]

2'-F-N2-ibu-2'-ara-dG
[CAS]

308356-20-9
[Synonyms]

2'-F-N2-ibu-2'-ara-dG
N2-iso-Butyroyl-2'-fluoro-2'-deoxyarabinoguanosine
Propanamide, N-[9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-6,9-dihydro-6-oxo-1H-purin-2-yl]-2-methyl-
[Molecular Formula]

C14H18FN5O5
[MOL File]

308356-20-9.mol
[Molecular Weight]

355.33
Chemical PropertiesBack Directory
[density ]

1.78±0.1 g/cm3(Predicted)
[pka]

8.68±0.20(Predicted)
Hazard InformationBack Directory
[Uses]

N2-iso-Butyroyl-2’-fluoro-2’-deoxyarabinoguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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