| Identification | Back Directory | [Name]
ALOESIN | [CAS]
30861-27-9 | [Synonyms]
ALOESIN
Aloeresin
Aloeresin B
Aloe resin B
8-β-D-Glucopyranosyl-7-hydroxy-5-methyl-2-(2-oxopropyl)-4H-1-benzopyran-4-one
2-(2-Oxopropyl)-5-methyl-7-hydroxy-8-(β-D-glucopyranosyl)-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one, 8-β-D-glucopyranosyl-7-hydroxy-5-methyl-2-(2-oxopropyl)-
4H-1-Benzopyran-4-one, 8-.beta.-D-glucopyranosyl-7-hydroxy-5-methyl-2-(2-oxopropyl)- | [Molecular Formula]
C19H22O9 | [MDL Number]
MFCD00869744 | [MOL File]
30861-27-9.mol | [Molecular Weight]
394.37 |
| Chemical Properties | Back Directory | [Boiling point ]
628.0±55.0 °C(Predicted) | [density ]
1.500±0.06 g/cm3(Predicted) | [storage temp. ]
Inert atmosphere,2-8°C | [solubility ]
DMSO:122.67(Max Conc. mg/mL);311.05(Max Conc. mM)
DMF:20.0(Max Conc. mg/mL);50.71(Max Conc. mM)
Ethanol:10.0(Max Conc. mg/mL);25.36(Max Conc. mM)
PBS (pH 7.2):5.0(Max Conc. mg/mL);12.68(Max Conc. mM) | [form ]
Pale yellow to brown powder. | [pka]
6.58±0.40(Predicted) | [color ]
White to off-white | [Cosmetics Ingredients Functions]
SKIN CONDITIONING | [LogP]
0.640 (est) |
| Hazard Information | Back Directory | [Chemical Properties]
White needle-shaped crystals, soluble in methanol, ethanol, DMSO and other organic solvents. | [Uses]
Aloeresin is an aromatic chromone present in various Aloe Species has shown potential beneficial effects on indexes related to pre-diabetic states including metabolic syndrome. | [Definition]
ChEBI: Aloesin is a member of chromones. | [in vivo]
Aloesin (injection; 20?mg/kg or 40?mg/kg; once daily; 7 w) inhibits tumor growth in a Xenograft model of ovarian cancer[1]. | Animal Model: | 6-week-old athymic nude mice injected with SKOV3 cells | | Dosage: | 20?mg/kg or 40?mg/kg | | Administration: | Injection; 20?mg/kg or 40?mg/kg; once daily; 7 weeks | | Result: | Reduced volumes and average weights of dissected tumors significantly compared with the control group. |
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