| Identification | Back Directory | [Name]
L-Lysine, L-arginyl-L-phenylalanyl-L-alanyl-L-arginyl-L-lysylglycyl-L-alanyl-L-leucyl-L-arginyl-L-glutaminyl-L-lysyl-L-asparaginyl-L-valyl-L-histidyl-L-α-glutamyl-L-valyl- | [CAS]
309247-48-1 | [Synonyms]
L-Lysine, L-arginyl-L-phenylalanyl-L-alanyl-L-arginyl-L-lysylglycyl-L-alanyl-L-leucyl-L-arginyl-L-glutaminyl-L-lysyl-L-asparaginyl-L-valyl-L-histidyl-L-α-glutamyl-L-valyl- | [Molecular Formula]
C89H153N33O22 | [MOL File]
309247-48-1.mol | [Molecular Weight]
2037.41 |
| Hazard Information | Back Directory | [Uses]
Protein Kinase C (19-35) Peptide is the PKC pseudosubstrate inhibitor/region. Protein Kinase C (19-35) Peptide possibly blocks the substrate-binding site in its kinase domain, makes the cytoplasmic form of PKC inactive[1][2]. | [References]
[1] Steiner J, et al. The effect of acute ethanol (EtOH) exposure on protein kinase C (PKC) activity in anterior pituitary. Alcohol. 1997 May-Jun;14(3):209-11. DOI:10.1016/s0741-8329(96)00113-9
[2] Mosior M, et al. Peptides that mimic the pseudosubstrate region of protein kinase C bind to acidic lipids in membranes. Biophys J. 1991 Jul;60(1):149-59. DOI:10.1016/S0006-3495(91)82038-0
[3] Laudanna C, et al. Evidence of zeta protein kinase C involvement in polymorphonuclear neutrophil integrin-dependent adhesion and chemotaxis. J Biol Chem. 1998 Nov 13;273(46):30306-15. DOI:10.1074/jbc.273.46.30306 |
|
|