| Identification | Back Directory | [Name]
7-bromoquinoline-4-carboxylic acid | [CAS]
31009-04-8 | [Synonyms]
7-bromoquinoline-4-carboxylic acid
4-Quinolinecarboxylic acid, 7-bromo- | [EINECS(EC#)]
202-110-6 | [Molecular Formula]
C10H6BrNO2 | [MOL File]
31009-04-8.mol | [Molecular Weight]
252.06 |
| Hazard Information | Back Directory | [Uses]
7-Bromoquinoline-4-carboxylic acid is an organic compound primarily used for chemical synthesis[1]. | [Synthesis]
The general procedure for the synthesis of 7-bromoquinoline-4-carboxylic acid from the compound (CAS:1219834-21-5) was as follows: compound 1 (1 g) was dissolved in 10 mL of nitrobenzene and heated to reflux overnight for decarboxylation reaction. After completion of the reaction, the reaction mixture was concentrated under reduced pressure and the resulting solid was purified by recrystallization from hexane to give the final brown solid product in 67% (570 mg) yield. | [References]
[1] Mai I Shahin, et al. Synthesis and biological evaluation of novel 2-oxo-1,2-dihydroquinoline-4-carboxamide derivatives for the treatment of esophageal squamous cell carcinoma. Eur J Med Chem. 2018 Jul 15:155:516-530. DOI:10.1016/j.ejmech.2018.05.042 |
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| Company Name: |
Cochemical Ltd.
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| Telephone: |
029-86115547 17791676824 |
| Website: |
http://www.cochemical.com |
| Company Name: |
Shaanxi Dideu Medichem Co. Ltd
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+86-029-81138252 +86-173 9270 1263 |
| Website: |
https://www.chemicalbook.com/manufacturer/shaanxi-dideu-medichem-222/ |
| Company Name: |
Energy Chemical
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021-58432009 400-005-6266 |
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http://www.energy-chemical.com |
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