| Identification | Back Directory | [Name]
Ethanamine, 2-(3-pyridinyloxy)- (9CI) | [CAS]
310880-25-2 | [Synonyms]
3-(2-AMinoethoxy)pyridine
2-(3-Pyridinyloxy)ethylamine
2-(3-Pyridinyloxy)ethanamine
2-(Pyridin-3-yloxy)ethanaMine
Ethanamine, 2-(3-pyridinyloxy)-
2-(pyridin-3-yloxy)ethanamine HCl
Ethanamine, 2-(3-pyridinyloxy)- (9CI)
2-(pyridin-3-yloxy)ethanamine dihydrochloride | [Molecular Formula]
C7H10N2O | [MDL Number]
MFCD12192564 | [MOL File]
310880-25-2.mol | [Molecular Weight]
138.17 |
| Chemical Properties | Back Directory | [Boiling point ]
258.8±20.0 °C(Predicted) | [density ]
1.089±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C(protect from light) | [pka]
8.08±0.10(Predicted) | [Appearance]
Colorless to light yellow Liquid | [InChI]
InChI=1S/C7H10N2O/c8-3-5-10-7-2-1-4-9-6-7/h1-2,4,6H,3,5,8H2 | [InChIKey]
WKMLARMIRUVDDF-UHFFFAOYSA-N | [SMILES]
C(N)COC1=CC=CN=C1 |
| Hazard Information | Back Directory | [Synthesis]
General procedure for the synthesis of 3-(2-aminoethoxy)pyridine using 2-(pyridin-3-yloxy)acetonitrile (CAS: 266348-17-8) as starting material: 2-(pyridin-3-yloxy)acetonitrile (100 mg, 0.75 mmol), K2CO3 (103 mg, 0.75 mmol), DMSO was sequentially added in a 100 mL two-neck flask (0.1 mL) and H2O (2 mL). The reaction system was placed in an ice bath and 30% H2O2 (0.1 mL) was added slowly and dropwise. Subsequently, the reaction mixture was stirred at room temperature for 5 min, after which the solvent was removed by evaporation. The crude product was purified by column chromatography using ethyl acetate as eluent to give the final white solid product 3-(2-aminoethoxy)pyridine (62.2 mg, 55% yield). | [References]
[1] Patent: TWI607995, 2017, B. Location in patent: Page/Page column 183 |
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