| Identification | Back Directory | [Name]
1-Heptanone, 1,1'-(2,4,6-trihydroxy-1,3-phenylene)bis- | [CAS]
3118-36-3 | [Synonyms]
Anti-MRSA agent 8
1-Heptanone, 1,1'-(2,4,6-trihydroxy-1,3-phenylene)bis- | [Molecular Formula]
C20H30O5 | [MOL File]
3118-36-3.mol | [Molecular Weight]
350.449 |
| Hazard Information | Back Directory | [Uses]
Anti-MRSA agent 8 (Compound 7g) is a DAPG derivative with strong antibacterial activity. Anti-MRSA agent 8 assertes its activity by targeting bacterial cell membranes. Anti-MRSA agent 8 can be used for the research of methicillin-resistant Staphylococcus aureus (MRSA)[1]. | [References]
[1] Zhong Y, et al. 2,4-Diacetylphloroglucinol (DAPG) derivatives rapidly eradicate methicillin-resistant staphylococcus aureus without resistance development by disrupting membrane. Eur J Med Chem. 2023 Sep 29;261:115823. DOI:10.1016/j.ejmech.2023.115823 |
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