| Identification | Back Directory | [Name]
HEMICHOLINIUM-3 | [CAS]
312-45-8 | [Synonyms]
hc-3
Dibromide
hemicholine
hemicholiniumbromide
hemicholiniumdibromide
hemicholinium-3bromide
hemicholinium-3dibromide
2,2'-(4,4'-biphenylene)bis(2-hydroxy-4,4-dimethylmorpholinium) dibromide
2,2’-(4,4’-biphenylylene)bis(2-hydroxy-4,4-dimethyl-morpholiniudibromide
2,2’-(1,1’-biphenyl)-4,4’-diylbis(2-hydroxy-4,4-dimethyl-morpholinium)dibrom
2-[4-[4-(2-hydroxy-4,4-dimethylmorpholin-4-ium-2-yl)phenyl]phenyl]-4,4-dimethylmorpholin-4-ium-2-ol dibromide
2-[4-[4-(2-hydroxy-4,4-dimethyl-morpholin-4-ium-2-yl)phenyl]phenyl]-4,4-dimethyl-morpholin-4-ium-2-ol dibromide
HACU,Choline,receptor,system,Hemicholinium dibromide,Inhibitor,transporter,ACh,Nicotinic,Hemicholinium 3,Hemicholinium3,inhibit,nervous,Enteric,neuromuscular,acetylcholine,Cholinesterase (ChE) | [EINECS(EC#)]
206-227-3 | [Molecular Formula]
C24H34N2O4.2Br | [MDL Number]
MFCD00011978 | [MOL File]
312-45-8.mol | [Molecular Weight]
574.351 |
| Safety Data | Back Directory | [Hazard Codes ]
T | [Risk Statements ]
23/24/25-36/37/38 | [Safety Statements ]
26-36/37/39-45 | [RIDADR ]
UN 2811 6.1/PG 2
| [WGK Germany ]
3
| [RTECS ]
QF2450000
| [HazardClass ]
6.1(b) | [PackingGroup ]
III | [Toxicity]
LD50 i.p. in female mice: 0.048-0.082 mg/kg (DiAugustine, Haarstad) |
| Hazard Information | Back Directory | [Uses]
Acetylcholine stores depletor | [Uses]
Research tool as cholinergic probe, to deplete acetylcholine stores. | [Biochem/physiol Actions]
Hemicholinium-3 plays a role in blocking the neuronal choline uptake thereby inhibiting acetylcholine synthesis in the brain. |
|
| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
|