| Identification | Back Directory | [Name]
Ethane, 1,2-bis(2-bromoethoxy)- | [CAS]
31255-10-4 | [Synonyms]
31255-10-4
CAS_31255-10-4
Br-PEG2-bromide
Bromo-PEG3-bromide
Bromo-PEG2-bromide
1,2-Bis(2-bromoethoxy)ethane
Ethane, 1,2-bis(2-bromoethoxy)- | [Molecular Formula]
C6H12Br2O2 | [MDL Number]
MFCD00466590 | [MOL File]
31255-10-4.mol | [Molecular Weight]
275.97 |
| Chemical Properties | Back Directory | [Boiling point ]
140 °C(Press: 12 Torr) | [density ]
1.6777 g/cm3 | [storage temp. ]
-20°C Freezer, Under inert atmosphere | [solubility ]
Chloroform, Ethyl Acetate (Slightly) | [form ]
Oil | [color ]
Colourless | [Stability:]
Moisture Sensitive | [InChI]
InChI=1S/C6H12Br2O2/c7-1-3-9-5-6-10-4-2-8/h1-6H2 | [InChIKey]
UOWNEWCMPHICQH-UHFFFAOYSA-N | [SMILES]
C(OCCBr)COCCBr |
| Hazard Information | Back Directory | [Description]
Bromo-PEG2-bromide is a PEG linker containing two bromide groups. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media. | [Uses]
Bromo-PEG2-bromide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] Chen TH, et al. Metal-organic frameworks constructed from crown ether-based 1,4-benzenedicarboxylic acid derivatives. Dalton Trans. 2016 Feb 21;45(7):3063-9. DOI:10.1039/c5dt04316f |
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Rhawn Reagent
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