| Identification | Back Directory | [Name]
2-AMINOMETHYL-3-FLUOROPYRIDINE DIHYDROCHLORIDE | [CAS]
312904-49-7 | [Synonyms]
2-AMinoMethyl-3-fluoropyr...
3-Fluoro-2-pyridineMethanaMine 2HCl
2-(Aminomethyl)-3-fluoropyridine 2HCl
2-AMinoMethyl-3-fluoropyridine hydrochloride
2-AMINOMETHYL-3-FLUOROPYRIDINE DIHYDROCHLORIDE
(3-fluoro-2-pyridyl)methanamine dihydrochloride
C-(3-FLUOROPYRIDIN-2-YL)-METHAMINE HYDROCHLORIDE
(3-Fluoropyridin-2-yl)MethanaMine dihydrochloride | [Molecular Formula]
C6H9Cl2FN2 | [MDL Number]
MFCD09954760 | [MOL File]
312904-49-7.mol | [Molecular Weight]
162.59 |
| Chemical Properties | Back Directory | [storage temp. ]
Inert atmosphere,Room Temperature | [Appearance]
Light yellow to light brown Solid | [InChI]
InChI=1S/C6H7FN2.ClH/c7-5-2-1-3-9-6(5)4-8;/h1-3H,4,8H2;1H | [InChIKey]
ATBRZELHPCIJTK-UHFFFAOYSA-N | [SMILES]
C(C1N=CC=CC=1F)N.Cl |
| Hazard Information | Back Directory | [Uses]
2-Aminomethyl-3-fluoropyridine dihydrochloride is a key intermediate in the synthesis of thrombin inhibitors. | [References]
[1] Papaioannou*, N., Fray*, M. J., Rennhack, A., Sanderson, T. J., & Stokes, J. E. (2020). Regioselective Amidomethylation of 4-Chloro-3-fluoropyridine by Metalation and Minisci-Type Reactions. <i>The Journal of Organic Chemistry</i>, <i>85 19</i>, 12067–12079. https://doi.org/10.1021/acs.joc.0c01168
[2] Ashwood, M. S., Alabaster, R. J., Cottrell, I. F., Cowden, C. J., Davies, A. J., Dolling, U. H., Emerson, K. M., Gibb, A. D., Hands, D., Wallace, D. J., & Wilson, R. D. (2004). Development of a Scaleable Synthesis of a 3-Aminopyrazinone Acetamide Thrombin Inhibitor. <i>Organic Process Research &amp; Development</i>, <i>8 2</i>, 192–200. https://doi.org/10.1021/op0341420
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| Company Name: |
Tetranov Biopharm
|
| Telephone: |
13526569071 |
| Website: |
http://www.leadmedpharm.com/index.html |
| Company Name: |
Wuxi AppTec
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| Telephone: |
022-59987777 13552403979 |
| Website: |
www.labnetwork.com |
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