| Identification | Back Directory | [Name]
panepoxydone | [CAS]
31298-54-1 | [Synonyms]
Panepoxydone from Lentinus conatus, >=95% (HPLC)
(1S,6S)-5β-Hydroxy-3-[(R)-1-hydroxy-3-methyl-2-butenyl]-7-oxabicyclo[4.1.0]hept-3-en-2-one
(1β,6β)-3-[(1R)-1-Hydroxy-3-methyl-2-butenyl]-5β-hydroxy-7-oxabicyclo[4.1.0]hepta-3-ene-2-one
(1S,5R,6S)-5-Hydroxy-3-[(1S)-1-hydroxy-3-methyl-2-buten-1-yl]-7-oxabicyclo[4.1.0]hept-3-en-2-one
7-Oxabicyclo[4.1.0]hept-3-en-2-one, 5-hydroxy-3-[(1S)-1-hydroxy-3-methyl-2-buten-1-yl]-, (1S,5R,6S)- | [Molecular Formula]
C11H14O4 | [MOL File]
31298-54-1.mol | [Molecular Weight]
210.23 |
| Chemical Properties | Back Directory | [Boiling point ]
437.9±45.0 °C(Predicted) | [density ]
1.338±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
DMSO: soluble10mg/mL | [form ]
powder | [pka]
12.67±0.40(Predicted) |
| Hazard Information | Back Directory | [Biochem/physiol Actions]
Panepoxydone is a fungal metabolite that inhibits NF-κB transcription factor by preventing IκB phosphorylation, thus inhibiting the release of NF-κB from the IκB : NF-κB complex and its translocation into the nucleus. Panepoxydone also has antimalarial, cytotoxic activities and anti-parasitic activity against Trypanosoma cruzi. |
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