ChemicalBook--->CAS DataBase List--->313477-85-9

313477-85-9

313477-85-9 Structure

313477-85-9 Structure
IdentificationBack Directory
[Name]

6-CHLORO-2-IODOPURINE-9-RIBOSIDE
[CAS]

313477-85-9
[Synonyms]

108679
6-Chloro-2-iodopurine riboside
6-CHLORO-2-IODOPURINE-9-RIBOSIDE
-2-((6-Chloro-2-iodo-9H-purin-9-yl)
2-iodo-6-chloro-9-(β-D-ribofuranosyl)purine
6-chloro-2-iodo-9-β-D-ribofuranosyl-1H-purine
6-Chloro-2-iodo-9-beta-D-ribofuranosyl purine
9H-Purine, 6-chloro-2-iodo-9-β-D-ribofuranosyl-
6-Chloro-2-iodo-9-beta-D-ribofuranosyl-9H-purine
6-Chloro-2-iodopurine riboside,6-Chloro-2-iodo-9-beta-D-ribofuranosyl purine
(2R,3R,4S,5R)-2-(6-chloro-2-iodo-9H-purin-9-yl)-5-(hydroxyMethyl)tetrahydrofuran-3,4-diol
(2S,3R,4S,5R)-2-((6-Chloro-2-iodo-9H-purin-9-yl)-oxy)-5-(hydroxymethyl)tetrahydrofuran-3,4-dio
(2S,3R,4S,5R)-2-((6-Chloro-2-iodo-9H-purin-9-yl)-oxy)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
[Molecular Formula]

C10H10ClIN4O4
[MDL Number]

MFCD23843805
[MOL File]

313477-85-9.mol
[Molecular Weight]

412.57
Chemical PropertiesBack Directory
[Boiling point ]

715.7±70.0 °C(Predicted)
[density ]

2.60±0.1 g/cm3(Predicted)
[storage temp. ]

2-8°C
[pka]

13.00±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

9H-Purine, 6-chloro-2-iodo-9-β-D-ribofuranosyl- (6-CHLORO-2-IODOPURINE-9-RIBOSIDE) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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