| Identification | Back Directory | [Name]
7,8-DIHYDRO-8-OXOADENOSINE-3':5'-CYCLIC MONOPHOSPHATE | [CAS]
31356-95-3 | [Synonyms]
8-OH-cAMP
8-OH-CAMP, NA
8-Hydroxy-cyclic AMP
8-OH-CAMP SODIUM SALT
8-hydroxyadenosine 3':5'-cyclic monophosphate
8-Hydroxyadenosine-3'',5''-monophosphoric acid
8-hydroxyadenosine3’:5’-cyclic*monophosphoricac
8-HYDROXYADENOSINE 3':5'-CYCLIC MONOPHOSPHORIC ACID
7,8-DIHYDRO-8-OXOADENOSINE-3':5'-CYCLIC MONOPHOSPHATE
8-HYDROXYADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
ADENOSINE 3',5'-CYCLIC MONOPHOSPHATE, 8-HYDROXY-, SODIUM SALT
Adenosine, 7,8-dihydro-8-oxo-, cyclic 3',5'-(hydrogen phosphate)
8-hydroxyadenosine-3’,5’-cyclicmonophosphate,sodiumsalt(8-oh-camp)
8-Hydroxy-cyclic AMP, 7,8-Dihydro-8-oxoadenosine 3μ:5μ-cyclic monophosphate | [Molecular Formula]
C10H12N5O7P | [MDL Number]
MFCD00079352 | [MOL File]
31356-95-3.mol | [Molecular Weight]
345.21 |
| Hazard Information | Back Directory | [Uses]
8-OH-cAMP (8-Hydroxy-cAMP) is a polar, membrane-impermeable cyclic adenosine monophosphate analog that is resistant to mammalian cyclic nucleotide-dependent phosphodiesterases. As a polar PKA agonist, 8-OH-cAMP is used to study the role of cAMP in the development and progression of cardiovascular and metabolic diseases[1]. | [References]
[1] Waidmann O, et al. Inhibition of the equilibrative nucleoside transporter 1 and activation of A2A adenosine receptors by 8-(4-chlorophenylthio)-modified cAMP analogs and their hydrolytic products[J]. Journal of biological chemistry, 2009, 284(47): 32256-32263. DOI:10.1074/jbc.M109.056622 |
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