| Chemical Properties | Back Directory | [Boiling point ]
540.3±60.0 °C(Predicted) | [density ]
1.26±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
7.59±0.50(Predicted) | [color ]
Yellow to orange |
| Hazard Information | Back Directory | [Uses]
COH34 analog 1, a metabolite, is an oxidized analog of COH34. COH34 is a potent poly(ADP-ribose) glycohydrolase (PARG) inhibitor[1]. | [References]
[1] Chen SH, et al. Targeting dePARylation selectively suppresses DNA repair-defective and PARP inhibitor-resistant malignancies. Sci Adv. 2019 Apr 10;5(4):eaav4340. DOI:10.1126/sciadv.aav4340 |
|
|