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314248-24-3

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314248-24-3 Structure

314248-24-3 Structure
IdentificationBack Directory
[Name]

COH34 analog 1
[CAS]

314248-24-3
[Synonyms]

COH34 analog 1
[Molecular Formula]

C18H15NO3S
[MDL Number]

MFCD00585073
[MOL File]

314248-24-3.mol
[Molecular Weight]

325.38
Chemical PropertiesBack Directory
[Boiling point ]

540.3±60.0 °C(Predicted)
[density ]

1.26±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

7.59±0.50(Predicted)
[color ]

Yellow to orange
Hazard InformationBack Directory
[Uses]

COH34 analog 1, a metabolite, is an oxidized analog of COH34. COH34 is a potent poly(ADP-ribose) glycohydrolase (PARG) inhibitor[1].
[References]

[1] Chen SH, et al. Targeting dePARylation selectively suppresses DNA repair-defective and PARP inhibitor-resistant malignancies. Sci Adv. 2019 Apr 10;5(4):eaav4340. DOI:10.1126/sciadv.aav4340
Spectrum DetailBack Directory
[Spectrum Detail]

COH34 analog 1(314248-24-3)1HNMR
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