| Identification | Back Directory | [Name]
(4S)-4-Methyl-2-Pyrrolidinone | [CAS]
31551-66-3 | [Synonyms]
(S)-4-Methylpyrrolidin-2-one
(4S)-4-Methyl-2-Pyrrolidinone
(4S)-4-METHYLPYRROLIDIN-2-ONE
2-Pyrrolidinone, 4-methyl-, (S)-
2-Pyrrolidinone, 4-methyl-, (4S)-
(4S)-4-methylpyrrolidin-2-one - [M86462] | [Molecular Formula]
C5H9NO | [MDL Number]
MFCD19217125 | [MOL File]
31551-66-3.mol | [Molecular Weight]
99.13 |
| Hazard Information | Back Directory | [Synthesis]
General procedure for the synthesis of (S)-4-methylpyrrolidin-2-one from DL-3-methyl-Γ-butyrolactone:
(1) 4-methyl-2-oxotetrahydrofuran (10 g, 3.2 mol) and liquid ammonia (13 g, 4.3 mol) were added in a high-pressure reactor, and the reactor was sealed after cooling. The reactor was pressurized to 3 MPa and heated to 220 °C with continuous stirring. Upon completion of the reaction, stirring was stopped and the reaction mixture was allowed to cool naturally to room temperature, followed by depressurization. (S)-4-methyl-2-oxopyrrolidine (19.87 g, 4.2 mol) was finally obtained. | [References]
[1] Patent: CN108358825, 2018, A. Location in patent: Paragraph 0019 |
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| Company Name: |
AstaTech, Inc
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| Tel: |
(215) 785 3197 |
| Website: |
www.astatechinc.com |
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