| Identification | Back Directory | [Name]
URSODEOXYCHOLIC ACID SODIUM SALT | [CAS]
31687-65-7 | [Synonyms]
SODIUM URSODEOXYCHOLATE
URSODEOXYCHOLIC ACID SODIUM SALT
5BETA-CHOLANIC ACID-3ALPHA,7BETA-DIOL SODIUM SALT
3ALPHA,7BETA-DIHYDROXY-5BETA-CHOLANIC ACID SODIUM SALT
5beta-Cholanic Acid-3alpha,7beta-diol Sodium Salt
3alpha,7beta-Dihydroxy-5beta-cholanic Acid Sodium Salt
Ursodeoxycholic Acid Sodium Salt | [Molecular Formula]
C24H39NaO4 | [MDL Number]
MFCD00065453 | [MOL File]
31687-65-7.mol | [Molecular Weight]
414.55 |
| Hazard Information | Back Directory | [Description]
Ursodeoxycholic acid (UDCA) is a secondary bile acid formed via epimerization of chenodeoxycholic acid (CDCA; Item No. 10011286).1,2 UDCA is also a metabolite of lithocholic acid (LCA; Item No. 20253) in human liver microsomes.3 It inhibits taurocholic acid (Item No. 16215) uptake in HeLa cells expressing recombinant sodium/taurocholate cotransporting polypeptide (NTCP) with an IC50 value of 3.6 μM.4 UDCA (50 μM) inhibits apoptosis induced by deoxycholic acid (DCA; Item Nos. 20756 | 18231) or ethanol in primary rat hepatocytes.5 Dietary administration of UDCA blocks DCA-induced increases in the number of TUNEL-positive hepatocytes in rats. Formulations containing UDCA have been used in the treatment of primary biliary cirrhosis.WARNING This product is not for human or veterinary use. |
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