ChemicalBook--->CAS DataBase List--->31868-18-5

31868-18-5

31868-18-5 Structure

31868-18-5 Structure
IdentificationBack Directory
[Name]

mexazolam
[CAS]

31868-18-5
[Synonyms]

Melex
CS 386
Sedoxil
mexazolam
mexazolam API
mexazolam USP/EP/BP
Mexazolam (1.0mg/ml in Acetonitrile)
MexazolamQ: What is Mexazolam Q: What is the CAS Number of Mexazolam
10-Chloro-2,3,7,11b-tetrahydro-3-methyl-11b-(o-chlorophenyl)oxazolo[3,2-d][1,4]benzodiazepin-6(5H)-one
10-chloro-11b-(2-chlorophenyl)-3-methyl-2,3,5,7-tetrahydro-[1,3]oxazolo[3,2-d][1,4]benzodiazepin-6-one
10-Chloro-11b-(2-chlorophenyl)-2,3,7,11b-tetrahydro-3-methyloxazolo[3,2-d][1,4]benzodiazepin-6(5H)-one
10-Chloro-11b-(o-chlorophenyl)-2,3,7,11b-tetrahydro-3-methyloxazolo[3,2-d][1,4]benzodiazepin-6(5H)-one
Oxazolo[3,2-d][1,4]benzodiazepin-6(5H)-one, 10-chloro-11b-(2-chlorophenyl)-2,3,7,11b-tetrahydro-3-methyl-
Oxazolo[3,2-d][1,4]benzodiazepin-6(5H)-one, 10-chloro-11b-(2-chlorophenyl)-2,3,7,11b-tetrahydro-3-methyl- (9CI)
[Molecular Formula]

C18H16Cl2N2O2
[MDL Number]

MFCD00866982
[MOL File]

31868-18-5.mol
[Molecular Weight]

363.24
Chemical PropertiesBack Directory
[Melting point ]

172-175°
[Boiling point ]

522.2±50.0 °C(Predicted)
[density ]

1.3817 (rough estimate)
[refractive index ]

1.6100 (estimate)
[pka]

6.69(at 25℃)
Hazard InformationBack Directory
[Description]

Mexazolam is a benzodiazepine anxiolytic closely related to flutazolam. It is reported to be particularly effective against psychosomatic essential hypertension, peptic ulcer, irritable colon and autonomic dystonia.
[Originator]

Sankyo (Japan)
[Uses]

Mexazolam is a benzodiazepine derivative and have been investigated for its therapeutic value in treating anxiety. Mexazolam is known to be metabolized via the CYP3A4 pathway.
[Definition]

ChEBI: Mexazolam is an oxazolobenzodiazepine and a hemiaminal ether.
[Brand name]

MELEX
Safety DataBack Directory
[Toxicity]

LD50 in male, female mice; male, female rats (mg/kg): 4687, 4571, 810, 4500 orally; >6000, >6000, >4000, >4000 i.p. or s.c. (Masuda)
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