| Identification | Back Directory | [Name]
3-[4-Acetyl-2,3,6-trihydroxy-5-(3-methyl-2-butenyl)benzyl]-6-ethyl-4-hydroxy-5-methyl-2H-pyran-2-one | [CAS]
32274-52-5 | [Synonyms]
Arzanol
Homoarenol
Arzanol from Helichrysum italicum, >=98%
3-[4-Acetyl-2,3,6-trihydroxy-5-(3-methyl-2-butenyl)benzyl]-6-ethyl-4-hydroxy-5-methyl-2H-pyran-2-one
3-[[3-Acetyl-2,4,6-trihydroxy-5-(3-methyl-2-buten-1-yl)phenyl]methyl]-6-ethyl-4-hydroxy-5-methyl-2H-pyran-2-one
2H-Pyran-2-one, 3-[[3-acetyl-2,4,6-trihydroxy-5-(3-methyl-2-buten-1-yl)phenyl]methyl]-6-ethyl-4-hydroxy-5-methyl- | [Molecular Formula]
C22H26O7 | [MDL Number]
MFCD28168041 | [MOL File]
32274-52-5.mol | [Molecular Weight]
402.44 |
| Hazard Information | Back Directory | [Uses]
Arzanol has been used to test its effects as an autophagy modulator on HeLa cells and bladder cancer cells | [Biological Activity]
Arzanol is a polyphenol compound extracted from the plant Helichrysum italicum which grows in the Mediterranean area. Arzanol is known for its anti-inflammatory and antimicrobial activities. The anti-inflammatory activity was verified in an in-vivo r at model and was found to suppress the inflammatory response of the carrageenan-induced pleurisy. Moreover it was found to have an anti-HIV-1 activity. Arzanol inhibits COX-2-derived prostaglandin synthase-1 (mPGES-1) Inhibitor in-vitroin human stimulated monocytes.
Arzanol inhibits the activation of inflammatory transcription factor NFKBHIV replication in T cellsreleases of IL-1βIL-6IL-8and TNF-α,and biosynthesis of PGE2 by potentially inhibiting the mPGES-1 enzyme.''Arzanol is known for its anti-inflammatory and antimicrobial activities. The anti-inflammatory activity was verified in an in-vivo r |
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| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Merck KGaA
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| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
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