| Identification | Back Directory | [Name]
MEDICARPIN | [CAS]
32383-76-9 | [Synonyms]
MEDICARPIN
Nsc 350085
MEDICARPIN(RG)
(-)-medicarpin
3-HYDROXY-9-METHOXYPTEROCARPAN
(L)-De-o-methylhomopterocarpan
L-3-Hydroxy-9-methoxypterocarpan
6A,11A-Dihydro-9-methoxy-6H-benzofuro(3,2-C)(1)benzopyran-3-ol
6H-Benzofuro(3,2-C)(1)benzopyran-3-ol, 6A,11A-dihydro-9-methoxy-, cis- (8ci)
[6aR,11aR,(-)]-6a,11a-Dihydro-9-methoxy-6H-benzofuro[3,2-c][1]benzopyran-3-ol
6H-Benzofuro[3,2-c][1]benzopyran-3-ol, 6a,11a-dihydro-9-methoxy-, (6aR,11aR)- | [Molecular Formula]
C16H14O4 | [MDL Number]
MFCD00161527 | [MOL File]
32383-76-9.mol | [Molecular Weight]
270.28 |
| Chemical Properties | Back Directory | [Melting point ]
127.5-128.5° | [alpha ]
D22 -226° (chloroform) | [Boiling point ]
418.8±45.0 °C(Predicted) | [density ]
1.319±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder | [pka]
9.50±0.20(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
Medicarpin can be used to inhibit IL-8 release via interactions with toll-like receptor 4 and lipopolysaccharide. It can also be used to treat COVID-19. | [Definition]
ChEBI: (-)-medicarpin is the (-)-enantiomer of medicarpin. It has a role as a plant metabolite. It is an enantiomer of a (+)-medicarpin. | [target]
ROS | JNK | Bcl-2/Bax | TNF-α | NF-kB | p65 | P450 (e.g. CYP17) |
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