| Identification | Back Directory | [Name]
rac-Febrifugine Dihydrochloride | [CAS]
32434-42-7 | [Synonyms]
Febrifugine dihydrochloride
rac-Febrifugine Dihydrochloride
3-[3-[(2R,3S)-3-Hydroxy-2-piperidinyl]-2-oxopropyl]-4(3H)-quinazolinone dihydrochloride | [Molecular Formula]
C16H19N3O3 | [MDL Number]
MFCD27978373 | [MOL File]
32434-42-7.mol | [Molecular Weight]
301.34 |
| Chemical Properties | Back Directory | [Melting point ]
220-222 °C (decomp) | [storage temp. ]
-20°C | [solubility ]
H2O: soluble15mg/mL, clear | [form ]
powder | [color ]
off-white to gray to brown | [optical activity]
[α]/D 10 to 15°, c = 1 in H2O |
| Hazard Information | Back Directory | [Chemical Properties]
White Solid | [Uses]
rac-Febrifugine dihydrochloride is the salt of Febrifugine, a bioactive constituent of a Chinese medicinal herb that is characterized by its therapeutic activity regarding malaria, cancer, fibrosis and inflammatory diseases. | [Biochem/physiol Actions]
Febrifugine dihydrochloride exhibits strong antimalarial activity against Plasmodium falciparum, the most insidious malaria causative agent. The adverse effects of febrifugine include diarrhoea, vomiting and liver toxicity. |
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Sigma-Aldrich
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https://www.sigmaaldrich.cn |
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