| Identification | Back Directory | [Name]
2-Thiazolamine,4-cyclopropyl-(9CI) | [CAS]
324579-90-0 | [Synonyms]
ZERO/001322
ZINC00036924
Oprea1_723513
4-cyclopropylthiazol-2-aMine
4-Cyclopropyl-2-Thiazolamine
2-Thiazolamine, 4-cyclopropyl-
(4-cyclopropylthiazol-2-yl)amine
2-Thiazolamine,4-cyclopropyl-(9CI)
2-Amino-4-cyclopropyl-1,3-thiazole
4-cyclopropyl-1,3-thiazol-2-amine(SALTDATA: FREE) | [Molecular Formula]
C6H8N2S | [MDL Number]
MFCD01571854 | [MOL File]
324579-90-0.mol | [Molecular Weight]
140.21 |
| Chemical Properties | Back Directory | [Melting point ]
79-80℃ (water methanol ) | [Boiling point ]
292.1±9.0 °C(Predicted) | [density ]
1.369±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [pka]
5.27±0.10(Predicted) | [Appearance]
Light yellow to yellow Solid |
| Hazard Information | Back Directory | [Synthesis]
1-Cyclopropyl-2-bromoacetophenone (CAS [69267-75-0], 6.1 mmol, 1 g) and thiourea (6.1 mmol, 0.481 g) were mixed in 15 mL of methanol and the reaction mixture was refluxed overnight. After completion of the reaction, the solvent was removed by evaporation to afford 4-cyclopropyl-2-aminothiazole as an off-white solid (1.38 g, 100% yield). | [References]
[1] Patent: US2006/160857, 2006, A1. Location in patent: Page/Page column 56
[2] Patent: US2006/199960, 2006, A1. Location in patent: Page/Page column 25
[3] Journal of Medicinal Chemistry, 2017, vol. 60, # 8, p. 3352 - 3371
[4] Journal of Medicinal Chemistry, 2015, vol. 58, # 6, p. 2764 - 2778
[5] Patent: WO2005/110980, 2005, A2. Location in patent: Page/Page column 95 |
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| Company Name: |
J & K SCIENTIFIC LTD.
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| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
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