| Identification | Back Directory | [Name]
2-(2-ethoxyphenoxy)ethanol | [CAS]
3250-73-5 | [Synonyms]
SKL461
Avanafil Impurity 102
Tamsulosin Impurity 11
2-(2-ethoxyphenoxy)ethanol
Ethanol, 2-(2-ethoxyphenoxy)-
2-(2-ethoxyphenoxy)ethanol(WXC06349) | [Molecular Formula]
C10H14O3 | [MDL Number]
MFCD09675039 | [MOL File]
3250-73-5.mol | [Molecular Weight]
182.22 |
| Chemical Properties | Back Directory | [Melting point ]
38-39 °C | [Boiling point ]
128-130 °C(Press: 2 Torr) | [density ]
1.084±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [pka]
14.28±0.10(Predicted) |
| Hazard Information | Back Directory | [Synthesis]
The general procedure for the synthesis of 2-(2-ethoxyphenoxy)ethanol from ethylene carbonate and o-ethoxyphenol was as follows: o-ethoxyphenol (55.0 g, 0.398 mol), ethylene carbonate (70.1 g, 0.796 mol), and potassium carbonate (12.1 g, 0.088 mol) were added to toluene (550 mL), and the reaction was carried out at reflux for 24 hours. Upon completion of the reaction, ethyl acetate (275 mL) and saturated saline (550 mL) were added to the reaction mixture and extracted. After separation of the organic layer, it was dried with anhydrous sodium sulfate, filtered, and the filtrate was concentrated under reduced pressure to give 2-(2-ethoxyphenoxy)ethanol (72.5 g, 100% yield). | [References]
[1] Patent: KR101525493, 2015, B1. Location in patent: Paragraph 0072; 0106-0107 |
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| Company Name: |
parabiochem
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| Tel: |
025-83453382-8005 |
| Website: |
www.parabiochem.cn |
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