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325683-89-4

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325683-89-4 Structure

325683-89-4 Structure
IdentificationBack Directory
[Name]

3'-O-DMT-T-TNA
[CAS]

325683-89-4
[Synonyms]

3'-O-DMT-T-TNA
1-(3’-O-[4,4’-dimethoxytrityl]-α-L-threofuranosyl)-thymine
1-(3'-O-[4,4'-dimethoxytrityl]-alpha-L-threofuranosyl)-thymine
2,4(1H,3H)-Pyrimidinedione, 1-[(2R,3R,4S)-4-[bis(4-methoxyphenyl)phenylmethoxy]tetrahydro-3-hydroxy-2-furanyl]-5-methyl-
[Molecular Formula]

C30H30N2O7
[MOL File]

325683-89-4.mol
[Molecular Weight]

530.58
Chemical PropertiesBack Directory
[density ]

1.35±0.1 g/cm3(Predicted)
[pka]

9.55±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

1-(3’-O-[4,4’-Dimethoxytrityl]-alpha-L-threofuranosyl)-thymine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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