ChemicalBook--->CAS DataBase List--->326-59-0

326-59-0

326-59-0 Structure

326-59-0 Structure
IdentificationBack Directory
[Name]

METHYL 1,3-BENZODIOXOL-5-YLACETATE
[CAS]

326-59-0
[Synonyms]

NSC 105308
ASISCHEM D13375
Methyl 1,3-Benzodioxole-5-acetate
Methyl 1,3-benzodioxol-5-ylacetate
methyl2-(1,3-benzodioxol-5-yl)acetate
Methyl 2-(1,3-dioxaindan-5-yl)acetate
Methyl 4,5-(Methylenedioxy)phenylacetate
Methyl (3,4-Methylenedioxyphenyl)acetate
Methyl 2-(2H-1,3-benzodioxol-5-yl)acetate
1,3-Benzodioxole-5-acetic Acid Methyl Ester
BENZO[1,3]DIOXOL-5-YL-ACETIC ACID METHYL ESTER
[3,4-(Methylenedioxy)phenyl]acetic Acid Methyl Ester
METHYL 1,3-BENZODIOXOL-5-YLACETATE ISO 9001:2015 REACH
[Molecular Formula]

C10H10O4
[MDL Number]

MFCD08753503
[MOL File]

326-59-0.mol
[Molecular Weight]

194.18
Chemical PropertiesBack Directory
[Boiling point ]

278.3℃
[density ]

1.265
[refractive index ]

1.5430 (estimate)
[Fp ]

120.0℃
[InChI]

InChI=1S/C10H10O4/c1-12-10(11)5-7-2-3-8-9(4-7)14-6-13-8/h2-4H,5-6H2,1H3
[InChIKey]

HEMYXNDMAAOTCK-UHFFFAOYSA-N
[SMILES]

O1C2=CC=C(CC(OC)=O)C=C2OC1
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Acetone-->Podophyllotoxin
Safety DataBack Directory
[HazardClass ]

IRRITANT
Hazard InformationBack Directory
[Uses]

Methyl 1,3-benzodioxol-5-ylacetate is a reagent used to prepare pharmaceutically active Benzodioxole derivatives.
[Preparation]

1,3-Benzodioxole-5-acetic acid methyl ester is a lignan synthesized by the condensation of podophyllotoxin with acetone in the presence of an acid catalyst.
[Mode of action]

1,3-Benzodioxole-5-acetic acid methyl ester is a regioselective inhibitor of 5α→5β conversion. This inhibition leads to a decrease in the production of diene metabolites that may be carcinogenic, as well as a decrease in the production of podophyllotoxin and its derivatives (podophyllum alkaloids). It has been shown to have anti-inflammatory properties and to inhibit prostaglandin synthesis.
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