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IdentificationBack Directory
[Synonyms]

3,7-Cyclodecadien-1-one, 3,7-dimethyl-10-(1-methylethylidene)-, (3Z,7E)-
[Molecular Weight]

218.33
Chemical PropertiesBack Directory
[density ]

0.916±0.06 g/cm3(Predicted)
Hazard InformationBack Directory
[Uses]

cis,trans-Germacrone is a isomer of Germacrone (HY-N0440). Germacrone exhibits a wide range of antitumor, antioxidant and anti-inflammatory effects. Germacrone inhibits lung cancer cell proliferation and alters the Akt/MDM2/p53. Germacrone also arrests cell cycle at G1/S phase[1].
[References]

[1] Zhao Y, et al. Germacrone induces lung cancer cell apoptosis and cell cycle arrest via the Akt/MDM2/p53 signaling pathway. Mol Med Rep. 2021 Jun;23(6):452. DOI:10.3892/mmr.2021.12091
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