ChemicalBook--->CAS DataBase List--->327056-65-5

327056-65-5

327056-65-5 Structure

327056-65-5 Structure
IdentificationBack Directory
[Name]

2-Pyridinecarboximidamide,N-hydroxy-5-methoxy-(9CI)
[CAS]

327056-65-5
[Synonyms]

N-Hydroxy-5-MethoxypicoliniMidaMide
N-Hydroxy-5-methoxy-2-pyridinecarboximidamide
2-Pyridinecarboximidamide, N-hydroxy-5-methoxy-
2-Pyridinecarboximidamide,N-hydroxy-5-methoxy-(9CI)
[Molecular Formula]

C7H9N3O2
[MDL Number]

MFCD09910311
[MOL File]

327056-65-5.mol
[Molecular Weight]

167.17
Chemical PropertiesBack Directory
[Boiling point ]

317.5±52.0 °C(Predicted)
[density ]

1.32±0.1 g/cm3(Predicted)
[storage temp. ]

Inert atmosphere,Store in freezer, under -20°C
[pka]

14.21±0.50(Predicted)
Hazard InformationBack Directory
[Synthesis]

2-Cyano-5-methoxypyridine

89809-63-2

2-Pyridinecarboximidamide,N-hydroxy-5-methoxy-(9CI)

327056-65-5

The general procedure for the synthesis of N-hydroxy-5-methoxy-2-pyridine carboxamides from 5-methoxypicolinonitrile is as follows: using the standard method for the synthesis of kainamidoxime, an ethanol (4 mL) solution of 2-cyano-5-methoxypyridine (270 mg, 2.01 mmol), hydroxylamine hydrochloride (0.457 mL, 5 M, 2.28 mmol), and sodium hydroxide (0.230 mL, 10 N, 2.30 mmol) were mixed and heated to reflux for 24 hours. After standard post-treatment, 79 mg of 5-methoxypyridin-2-ylamidoxime was obtained in 24% yield.

[References]

[1] Patent: US2003/55085, 2003, A1
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