| Identification | Back Directory | [Name]
(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine | [CAS]
327623-37-0 | [Synonyms]
Aprepitant Impurity 1
Aprepitant Impurity 11
Fosaprepitant Impurity 30
Aprepitant Impurity 1 Hydrochloride
Aprepitant M2 Metabolite Enantiomer
Aprepitant M2 Metabolite (1S, 2S, 3R)-Isomer
Des-1,2,4-triazol-3-one-5-methyl(2S,3R,1&rsquo
Des-1,2,4-triazol-3-one-5-methyl (2S,3R,1'S)-Aprepitant
(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine
(2S,3R)-2-[(1S)-1-(3,5-bis-trifluoro-Methylphenyl)ethoxy]-3-(4-fluorophenyl)Morpholine
Morpholine, 2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-, (2S,3R)-
(2S,3R)-2-[(1S)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine hydrochloride | [Molecular Formula]
C20H18F7NO2 | [MOL File]
327623-37-0.mol | [Molecular Weight]
437.35 |
| Hazard Information | Back Directory | [Uses]
Des-1,2,4-triazol-3-one-5-methyl (2S,3R,1''S)-Aprepitant is an impurity of Aprepitant (A729800); a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Antiemetic. |
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| Company Name: |
Energy Chemical
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| Telephone: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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