| Identification | Back Directory | [Name]
RQIKIWFQNRRMKWKK | [CAS]
329306-46-9 | [Synonyms]
DT-5
PENETRATIN
RQIKIWFQNRRMKWKK
ANTENNAPEDIA PEPTIDE
H-RQIKIWFQNRRMKWKK-OH
H2N-RQIKIWFQNRRMKWKK-OH
DT-3 trifluoroacetate salt
DROSOPHILA ANTENNAPEDIA HOMEO-DOMAIN (43-58)
(DEFORMED)(CEPHALOTHORAX)(HOMEOBOX) FRAGMENT
ARG-GLN-ILE-LYS-ILE-TRP-PHE-GLN-ASN-ARG-ARG-MET-LYS-TRP-LYS-LYS
ARG-GLN-ILE-LYS-ILE-TRP-PHE-GLN-ASN-ARG-ARG-MET-LYS-TRP-LYS-LYS-OH | [Molecular Formula]
C152H258N52O28S | [MDL Number]
MFCD04974159 | [MOL File]
329306-46-9.mol | [Molecular Weight]
3294.07 |
| Chemical Properties | Back Directory | [density ]
1.43±0.1 g/cm3(Predicted) | [storage temp. ]
−20°C | [Sequence]
Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-Leu-Arg-Lys-Lys-Lys-Lys-Lys-His |
| Hazard Information | Back Directory | [Uses]
DT-3 is a membrane-permeable protein kinase G Iα (PKG Iα) inhibitory peptide and shows pharmacological blockade of the cGMP-PKG signalling[1]. | [References]
[1] Shinichi Takahashi, et al. Nitric oxide-cGMP-protein kinase G pathway negatively regulates vascular transient receptor potential channel TRPC6. J Physiol. 2008 Sep 1;586(17):4209-23. DOI:10.1113/jphysiol.2008.156083 |
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