| Identification | Back Directory | [Name]
PHF6 | [CAS]
329897-62-3 | [Synonyms]
PHF6
L-Lysine, L-valyl-L-glutaminyl-L-isoleucyl-L-valyl-L-tyrosyl-
(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-5-amino-2-[[(2S)-2-amino-3-methylbutanoyl]amino]-5-oxopentanoyl]amino]-3-methylpentanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]hexanoicacid | [Molecular Formula]
C36H60N8O9 | [MDL Number]
MFCD30597990 | [MOL File]
329897-62-3.mol | [Molecular Weight]
748.91 |
| Chemical Properties | Back Directory | [Boiling point ]
1153.9±65.0 °C(Predicted) | [density ]
1.210±0.06 g/cm3(Predicted) | [pka]
3.27±0.10(Predicted) | [Sequence]
Val-Gln-Ile-Val-Tyr-Lys |
| Hazard Information | Back Directory | [Uses]
PHF6 (VQIVYK) is a self-assembly sequence capable of initiating the full-length tau protein aggregation and is mapped to the third microtubule-binding repeat region of the tau protein[1]. | [References]
[1] Chinmaya Panda, et al. Aggregated Tau-PHF6 (VQIVYK) Potentiates NLRP3 Inflammasome Expression and Autophagy in Human Microglial Cells. Cell. 2021 Jun 30;10(7):1652. DOI:10.3390/cells10071652 |
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| Company Name: |
BOC Sciences
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| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
| Company Name: |
Phygene
|
| Tel: |
18059081430 |
| Website: |
www.phygene.com/ |
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