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329935-45-7

329935-45-7 Structure

329935-45-7 Structure
IdentificationBack Directory
[Name]

Methanone, [1,1'-biphenyl]-4-yl(4-phenyl-1-piperazinyl)-
[CAS]

329935-45-7
[Synonyms]

PROT-IN-1
WAY-356814
Biphenyl-4-yl-(4-phenyl-piperazin-1-yl)-methanone
1,1'-Biphenyl]-4-yl(4-phenyl-1-piperazinyl)methanone
1,1'-Biphenyl]-4-yl(4-phenyl-1-piperazinyl)methanone
Methanone, [1,1'-biphenyl]-4-yl(4-phenyl-1-piperazinyl)-
[Molecular Formula]

C23H22N2O
[MOL File]

329935-45-7.mol
[Molecular Weight]

342.43
Chemical PropertiesBack Directory
[Boiling point ]

549.4±50.0 °C(Predicted)
[density ]

1.160±0.06 g/cm3(Predicted)
[form ]

Solid
[pka]

3.09±0.10(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

PROT-IN-1 (Compound 2) is a proline transporter (PROT) inhibitor (IC50: 1.48 μM). PROT-IN-1 can be used for research of cognitive disorders[1].
[References]

[1] Zipp GG, et al. Novel inhibitors of the high-affinity L-proline transporter as potential therapeutic agents for the treatment of cognitive disorders. Bioorg Med Chem Lett. 2014 Aug 15;24(16):3886-90. DOI:10.1016/j.bmcl.2014.06.049
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