| Identification | Back Directory | [Name]
Methanone, [1,1'-biphenyl]-4-yl(4-phenyl-1-piperazinyl)- | [CAS]
329935-45-7 | [Synonyms]
PROT-IN-1 WAY-356814 Biphenyl-4-yl-(4-phenyl-piperazin-1-yl)-methanone 1,1'-Biphenyl]-4-yl(4-phenyl-1-piperazinyl)methanone 1,1'-Biphenyl]-4-yl(4-phenyl-1-piperazinyl)methanone Methanone, [1,1'-biphenyl]-4-yl(4-phenyl-1-piperazinyl)- | [Molecular Formula]
C23H22N2O | [MOL File]
329935-45-7.mol | [Molecular Weight]
342.43 |
| Chemical Properties | Back Directory | [Boiling point ]
549.4±50.0 °C(Predicted) | [density ]
1.160±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
3.09±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
PROT-IN-1 (Compound 2) is a proline transporter (PROT) inhibitor (IC50: 1.48 μM). PROT-IN-1 can be used for research of cognitive disorders[1]. | [References]
[1] Zipp GG, et al. Novel inhibitors of the high-affinity L-proline transporter as potential therapeutic agents for the treatment of cognitive disorders. Bioorg Med Chem Lett. 2014 Aug 15;24(16):3886-90. DOI:10.1016/j.bmcl.2014.06.049 |
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