ChemicalBook--->CAS DataBase List--->3303-31-9

3303-31-9

3303-31-9 Structure

3303-31-9 Structure
IdentificationBack Directory
[Name]

H-LEU-LEU-OH
[CAS]

3303-31-9
[Synonyms]

LL
LEU-LEU
NSC 89185
Leu-Leu-OH
L-LEU-L-LEU
H-LEU-LEU-OH
L-Leu-L-Leu-OH
leu-leu free base
L-LEUCYL-L-LEUCINE
L-Leucine, L-leucyl-
N-L-leucyl-L-leucine
Leu-Leu-OH≥ 96% (HPLC)
Leu-Leu.HCl|H-Leu-Leu-OH.HCl
-2-Amino-4-methylpentanamido)
(S)-2-((S)-2-Amino-4-methylpentanamido)-4-methylpentanoic acid
(S)-2-[[(S)-2-Amino-4-methylvaleryl]amino]-4-methylvaleric acid
(2S)-2-[(2S)-2-amino-4-methylpentanamido]-4-methylpentanoic acid
(2S)-2-[[(2S)-2-amino-4-methylpentanoyl]amino]-4-methylpentanoic acid
[EINECS(EC#)]

221-976-6
[Molecular Formula]

C12H24N2O3
[MDL Number]

MFCD00065185
[MOL File]

3303-31-9.mol
[Molecular Weight]

244.33
Chemical PropertiesBack Directory
[Melting point ]

270-272℃ (decomposition)
[Boiling point ]

432.7±30.0 °C(Predicted)
[density ]

1.051±0.06 g/cm3(Predicted)
[storage temp. ]

−20°C
[solubility ]

Methanol (Slightly, Heated), Water (Slightly, Sonicated)
[form ]

Solid
[pka]

3.16±0.10(Predicted)
[color ]

White to Off-White
[InChI]

InChI=1S/C12H24N2O3/c1-7(2)5-9(13)11(15)14-10(12(16)17)6-8(3)4/h7-10H,5-6,13H2,1-4H3,(H,14,15)(H,16,17)/t9-,10-/m0/s1
[InChIKey]

LCPYQJIKPJDLLB-UWVGGRQHSA-N
[SMILES]

C(O)(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)N
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P280-P301+P312-P302+P352-P305+P351+P338
[WGK Germany ]

3
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Chemical Properties]

White powder
[Uses]

Leu-Leu-OH (L-Leucyl-L-leucine), a Leu derivative, is a neutral dipeptide that can be used to study the functionality of dileucine motifs[1].
[Definition]

ChEBI: A dipeptide formed from two L-leucine residues.
[Biological Activity]

Leucylleucine (Leu-Leu) may be used to study the functionality of dileucine motifs such as the motif responsible for internalization and targeting of vesicular acetylcholine transporter and clathrin adaptors AP-1 and AP-2.
[References]

[1] Matthews DM, et al. Uptake of L-leucyl-L-leucine and glycylsarcosine by hamster jejunum in vitro. Clin Sci (Lond). 1983 Aug;65(2):177-84. DOI:10.1042/cs0650177
Spectrum DetailBack Directory
[Spectrum Detail]

H-LEU-LEU-OH(3303-31-9)13CNMR
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