| Identification | Back Directory | [Name]
Ramnodigin | [CAS]
33156-28-4 | [Synonyms]
Ramnodigin
Ramnodiginum
Unii-Z8sry7br30
Ramnodigin [inn]
14-Hydroxy-3beta-((2,3,6-trihydroxy-alpha-L-erythro-hexopyranosyl)oxy)-5beta-card-20(22)-enolide
Card-20(22)-enolide, 14-hydroxy-3-[[(2R,5R,6S)-tetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl]oxy]-, (3β,5β)- | [Molecular Formula]
C29H44O6 | [MOL File]
33156-28-4.mol | [Molecular Weight]
488.661 |
| Hazard Information | Back Directory | [Uses]
HOE 689 (Ramnodigin) is an analog of Digitoxin (HY-B1357). HOE 689 exhibits cytotoxicity to lung cancer cells and induces apoptosis in cancer cell NCI-H460 with an IC50 of 52 nM[1]. | [References]
[1] Wang HY, et al., C5'-Alkyl Substitution Effects on Digitoxigenin α-l-Glycoside Cancer Cytotoxicity. ACS Med Chem Lett. 2011 Apr 14;2(4):259-263. DOI:10.1021/ml100291n |
|
| Company Name: |
Leancare Ltd.
|
| Tel: |
+33 962096793 |
| Website: |
www.leancare.co.uk |
|