| Identification | Back Directory | [Name]
Ecabet | [CAS]
33159-27-2 | [Synonyms]
Ecabet
12-Sulfodehydroabietic acid
Abietic acid, dehydro-6-sulfo- (6CI)
13-Isopropyl-12-sulfopodocarpa-8,11,13-trien-15-oic acid
Podocarpa-8,11,13-trien-15-oic acid, 13-isopropyl-12-sulfo- (8CI)
1-Phenanthrenecarboxylic acid, 1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-6-sulfo-, (1R,4aS,10aR)-
1-Phenanthrenecarboxylic acid, 1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-6-sulfo-, [1R-(1α,4aβ,10aα)]- | [Molecular Formula]
C20H28O5S | [MDL Number]
MFCD11044526 | [MOL File]
33159-27-2.mol | [Molecular Weight]
380.5 |
| Chemical Properties | Back Directory | [alpha ]
D25 +72.4° (c = 2.5 in alcohol) | [density ]
1.241±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [pka]
-0.31±0.60(Predicted) |
| Hazard Information | Back Directory | [Uses]
Ecabet sodium (TA-2711) is currently applied to some clinical gastrointestinal disease by inhibiting the ROS production and improving Helicobacter pylori eradication[1]. Ecabet sodium reduces apoptosis[2] | [Definition]
ChEBI: Ecabet is a diterpenoid. | [References]
[1] Wang Y, et al. Efficacy and safety of ecabet sodium as an adjuvant therapy for Helicobacter pylori eradication: a systematic review and meta-analysis. Helicobacter. 2014 Oct;19(5):372-81. DOI:10.1111/hel.12136
[2] Rah YC, et al. Ecabet sodium alleviates neomycin-induced hair cell damage. Free Radic Biol Med. 2015 Dec;89:1176-83. PMID:265617 |
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