ChemicalBook--->CAS DataBase List--->33173-53-4

33173-53-4

33173-53-4 Structure

33173-53-4 Structure
IdentificationBack Directory
[Name]

4-Azido-L-phenylalanine
[CAS]

33173-53-4
[Synonyms]

H-PHE(4-N3)-OH
H-4-Azido-Phe-OH
H-L-Phe(4-N3)-OH
H-P-AZIDO-PHE-OH
H-PHE(4-AZIDO)-OH
L-Phe(4-azido)-OH
H-P-AZIDO-L-PHE-OH
4-azidophenylalanine
p-azidophenylanaline
P-AZIDO-PHENYLALANINE
p-Azido-L-phenylalanine
4-AZIDO-L-PHENYLALANINE
L-Phenylalanine, 4-azido-
4-Azido-L-phenylalanine HCl
4-Azido-L-phenylalanine≥ 98% (HPLC)
(S)-2-AMINO-3-P-AZIDOPHENYLPROPIONIC ACID
(S)-2-aMino-3-(4-azidophenyl)propanoic acid
(2S)-2-amino-3-(4-azidophenyl)propanoic acid
[Molecular Formula]

C9H10N4O2
[MDL Number]

MFCD00238100
[MOL File]

33173-53-4.mol
[Molecular Weight]

206.21
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[solubility ]

Water : 6.2 mg/mL (30.07 mM; ultrasonic and adjust pH to 6 with HCl);DMSO : 6 mg/mL (29.10 mM; ultrasonic and adjust pH to 6 with HCl)
[form ]

Solid
[color ]

White to yellow
[Appearance]

off-white solid
[InChI]

InChI=1/C9H10N4O2/c10-8(9(14)15)5-6-1-3-7(4-2-6)12-13-11/h1-4,8H,5,10H2,(H,14,15)/t8-/s3
[InChIKey]

NEMHIKRLROONTL-SBYBRXNCNA-N
[SMILES]

C(C1C=CC(N=[N+]=[N-])=CC=1)[C@H](N)C(=O)O |&1:10,r|
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501
[WGK Germany ]

WGK 3
[HS Code ]

2922498590
[Storage Class]

5.2 - Organic peroxides and self-reacting hazardous materials
[Hazard Classifications]

Self-react. C
Hazard InformationBack Directory
[Description]

4-Azido-L-phenylalanine (4AZP) is an unnatural amino acid analog of L-phenylalanine that contains an azide moiety. 4AZP-labeling is a fast, sensitive, and non-radioactive alternative to the traditional technique for detecting nascent protein synthesis.


4AZP is randomly incorporated into synthesizing protein instead of phenylalanine during translation. The resulting azide-labeled full-length proteins can be detected via copper-catalyzed click reaction (with fluorescent or biotin-labeled alkynes) or copper-free click reaction (with cycloalkynes) and used for subsequent microscopic imaging or purification tasks.

[Chemical Properties]

Off-white to brown powder
[Uses]

4-Azido-L-phenylalanine is an unnatural derivative of L-phenylalanine. It is a nonpolar, essential amino acid that naturally occurs in the human body and is also used to treat patients with depression.
[reaction suitability]

reaction type: click chemistry
reaction type: solution phase peptide synthesis
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