| Identification | Back Directory | [Name]
3,5-bis(4-fluorobenzylidene)-1-propyl-4-piperidinone | [CAS]
331839-29-3 | [Synonyms]
TachypleginA
Tachyplegin-A
Tachyplegin A
3,5-bis(4-fluorobenzylidene)-1-propyl-4-piperidinone | [Molecular Formula]
C22H21F2NO | [MOL File]
331839-29-3.mol | [Molecular Weight]
353.4 |
| Hazard Information | Back Directory | [Description]
TachypleginA is an Inhibitor of parasite motility and invasion. | [Uses]
TachypleginA can inhibit the motility of T. gondii by binding directly and covalently to C58 of TgMLC1，thereby causing a decrease in the activity of the parasite's myosin motor[1]. | [References]
[1] Leung JM, et al. Identification of T. gondii myosin light chain-1 as a direct target of TachypleginA-2, a small-molecule inhibitor of parasite motility and invasion. PLoS One. 2014;9(6):e98056. Published 2014 Jun 3. DOI:10.1371/journal.pone.0098056 |
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