| Identification | Back Directory | [Name]
D-Aminolevulinicacidmethylesterhydrochloride | [CAS]
33320-16-0 | [Synonyms]
methyl 5-aminolevulinate
methyl 5-amino-4-oxopentanoate
D-AminolevulinicacidmethylesterHCl
Pentanoic acid, 5-amino-4-oxo-, methyl ester | [Molecular Formula]
C6H11NO3 | [MDL Number]
MFCD08277630 | [MOL File]
33320-16-0.mol | [Molecular Weight]
145.16 |
| Hazard Information | Back Directory | [Uses]
Methyl aminolevulinate is an agent used as a sensitizer in photodynamic therapy (PDT). Methyl aminolevulinate is a proagent that can be metabolized to Protoporphyrin IX[1]. | [Definition]
ChEBI: The methyl ester of 5-aminolevulinic acid. A prodrug, it is metabolised to protoporphyrin IX, a photosensitizer, and is used in the photodynamic treatment of non-melanoma skin cancer (including basal cell carcinoma). Topical application (often as the hydro
hloride salt) results in an accumulation of protoporphyrin IX in the skin lesions to which the cream has been applied. Subsequent illumination with red light results in the generation of toxic singlet oxygen that destroys cell membranes and thereby kills t
e tumour cells. | [References]
[1] Methyl aminolevulinate, From Wikipedia |
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