ChemicalBook--->CAS DataBase List--->334658-24-1

334658-24-1

334658-24-1 Structure

334658-24-1 Structure
IdentificationBack Directory
[Name]

BODIPY CYCLOPAMINE
[CAS]

334658-24-1
[Synonyms]

BODIPY CYCLOPAMINE
[5-[(3,5-DiMethyl-2H-pyrrol-2-ylidene-κN)Methyl]-N-[6-[[2-[(3S,3'R,3'aS,6'S,6aS,6bS,7'aR,2'R,11aS,11bR)-1,2,3,3',3'a,4,5',6,6',6a,6b,7,7',7'a,8,11,11a,11b-octadecahydro-3-hydroxy-3',6',10,11b-tetraMethylspiro[9H-benzo[a]fluorene-9,2'(4'H)-furo[3,2-b]pyridin]-4'-yl]ethyl]aMino]-6-oxohexyl]-1H-pyrrole-2-propanaMidato-κN1]difluoro-boron
[Molecular Formula]

C49H70BF2N5O4
[MOL File]

334658-24-1.mol
[Molecular Weight]

841.919
Chemical PropertiesBack Directory
[Appearance]

Orange Powder
[Melting point ]

128-130°C
[storage temp. ]

Amber Vial, -20°C Freezer, Under Inert Atmosphere
[solubility ]

Chloroform (Slightly)
[form ]

Solid
[color ]

Red to Brown
[Stability:]

Light Sensitive
[InChIKey]

CQPRECBXTRAUSE-NJOUNXRJNA-N
[SMILES]

C1CC2(C)C3CC4=C(C)C5(O[C@H]6CC(C)CN(CCNC(=O)CCCCCNC(=O)CCc7[n]8[B-](F)(F)[N+]9=C(C)C=C(C)C9=Cc8cc7)C6C5C)CCC4C3CC=C2C[C@H]1O |&1:11,59,r|
Hazard InformationBack Directory
[Chemical Properties]

Orange Powder
[Uses]

Cyclopamine demonstrates teratogenic properties and has been shown to reverse effects ofoncogenic mutations in Smoothened and Patched.1 The Bodipy-Cyclopamine is a fluorescent derivative of Cyclopamine that retains potency in Shh signaling inhibiti
[Uses]

It is a fluorescent derivative of Cyclopamine that retains potency in Shh signaling inhibition (IC50=150nM).
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