ChemicalBook--->CAS DataBase List--->334994-34-2

334994-34-2

334994-34-2 Structure

334994-34-2 Structure
IdentificationBack Directory
[Name]

NORLEUAL
[CAS]

334994-34-2
[Synonyms]

NORLEUAL
[Molecular Formula]

C41H58N8O7
[MOL File]

334994-34-2.mol
[Molecular Weight]

774.96
Chemical PropertiesBack Directory
[Boiling point ]

1128.6±65.0 °C(Predicted)
[density ]

1.246±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[pka]

3.56±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

Norleual is an analog of angiotensin (Ang) IV. It competitively inhibited the binding of HGF to its receptor c-Met in mouse liver membranes. Ex vivo studies show that Norleual exhibited potent anti-angiogenic activity, as well as anticancer activity.
[in vivo]

Norleual (50 μg/kg; intraperitoneal injection; daily; for 2 weeks; C57BL/6 mice) suppresses pulmonary colonization by B16-F10 murine melanoma cells[1].

[storage]

Store at -20°C
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