| Identification | Back Directory | [Name]
1-Propanone, 1-(2,6-dihydroxyphenyl)- | [CAS]
3361-72-6 | [Synonyms]
1-Propanone, 1-(2,6-dihydroxyphenyl)- | [Molecular Formula]
C9H10O3 | [MOL File]
3361-72-6.mol | [Molecular Weight]
166.174 |
| Hazard Information | Back Directory | [Preparation]
Preparation by alkaline degradation of two substituted coumarins,
from 4-methyl-7-hydroxy-8-propionylcoumarin;
from 7-hydroxy-8-propionylcoumarin (m.p. 168°)
Also obtained by reaction of ethylmagnesium iodide on 2,6-dimethoxybenzonitrile, followed by cleavage of the ether linkages with aluminium chloride
Preparation by dehydrogenation of 2-propionylcyclohexane-1,3-dione
in the presence of 10% Pd/C in refluxing cumene overnight under nitrogen (57%)
in the presence of 5% Pd/C in tetraethyleneglycol dimethyl ether at 185°
Also obtained by decarboxylation of 4,6-dihydroxy-5-propionyl-1,3-benzenedi-carboxylic acid in refluxing water for 12 h (25%)
Also obtained from 2-chloro-2-propionyl-1,3-cyclohexanedione (m.p. 89°) by rearrangement in 10–20% hydrogen chloride-DMF at 120–130° for 15–20 min. |
|
|