| Hazard Information | Back Directory | [Description]
UK-414,495 acts as a potent, selective inhibitor of the enzyme neutral endopeptidase, which normally serves to break down the neuropeptide VIP. UK-414,495 is a drug used for the treatment of female sexual arousal disorder. | [Uses]
(Rac)-UK-414495 (example 7) is a potent neutral endopeptidase (NEP) inhibitor. (Rac)-UK-414495 causes potentiation of cAMP in the sexual genitalia of the female[1]. | [References]
[1] Graham NM, et, al. NEP inhibitors for the treatment of female sexual dysfunction. EP1481667A1. |
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