Identification | Back Directory | [Name]
N-[(2R,4R,5S)-5-[[(1,1-DiMethylethoxy)carbonyl]aMino]-4-[[(1,1-diMethylethyl)diMethylsilyl]oxy]-1-oxo-6-phenyl-2-(phenylMethyl)hexyl]-L-leucyl-L-phenylalaninaMide | [CAS]
338801-69-7 | [Synonyms]
N-[(2R,4R,5S)-5-[[(1,1-DiMethylethoxy)carbonyl]aMino]-4-[[(1,1-diMethylethyl)diMethylsilyl]oxy]-1-oxo-6-phenyl-2-(phenylMethyl)hexyl]-L-leucyl-L-phenylalaninaMide L-Phenylalaninamide, N-[(2R,4R,5S)-5-[[(1,1-dimethylethoxy)carbonyl]amino]-4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1-oxo-6-phenyl-2-(phenylmethyl)hexyl]-L-leucyl- (9CI) | [Molecular Formula]
C45H66N4O6Si | [MOL File]
338801-69-7.mol | [Molecular Weight]
787.11 |
Chemical Properties | Back Directory | [Boiling point ]
921.4±65.0 °C(Predicted) | [density ]
1.084±0.06 g/cm3(Predicted) | [solubility ]
Acetone, Acetonitrile | [pka]
12.01±0.46(Predicted) |
Hazard Information | Back Directory | [Uses]
N-[(2R,4R,5S)-5-[[(1,1-Dimethylethoxy)carbonyl]amino]-4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1-oxo-6-phenyl-2-(phenylmethyl)hexyl]-L-leucyl-L-phenylalaninamide is an intermediate in the synthesis of γ-Secretase Inhibitor, the enzyme complex that catalyzes the cleavage of the amyloid precursor protein (APP) to generate amyloid β-peptide (Aβ), the major causative agent in Alzheimer disease (AD). |
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Company Name: |
Energy Chemical
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Tel: |
021-58432009 400-005-6266 |
Website: |
http://www.energy-chemical.com |
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