| Identification | Back Directory | [Name]
3-amino-N-(4-fluorophenyl)-4-phenyl-6-(2-thienyl)thieno[2,3-b]pyridine-2-carboxamide | [CAS]
340817-81-4 | [Synonyms]
3-amino-N-(4-fluorophenyl)-4-phenyl-6-(2-thienyl)thieno[2,3-b]pyridine-2-carboxamide
Thieno[2,3-b]pyridine-2-carboxamide, 3-amino-N-(4-fluorophenyl)-4-phenyl-6-(2-thienyl)- | [Molecular Formula]
C24H16FN3OS2 | [MOL File]
340817-81-4.mol | [Molecular Weight]
445.53 |
| Chemical Properties | Back Directory | [Boiling point ]
612.6±55.0 °C(Predicted) | [density ]
1.429±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
10.56±0.70(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
AM-001 is a non-competitive inhibitor of Epac1 that blocks the activation of Rap1, a downstream effector of Epac1, in cultured cells. AM-001 can be used in heart disease-related research[1]. | [References]
[1] Laudette M,et al. Identification of a pharmacological inhibitor of Epac1 that protects the heart against acute and chronic models of cardiac stress. Cardiovasc Res. 2019 Oct 1;115(12):1766-1777. DOI:10.1093/cvr/cvz076 |
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