| Identification | Back Directory | [Name]
2'-O-Methyl-4-thiouridine | [CAS]
34218-80-9 | [Synonyms]
2'-O-Methyl-4-thiouridine
Uridine, 2'-O-methyl-4-thio- (8CI) | [Molecular Formula]
C10H14N2O5S | [MDL Number]
MFCD30570246 | [MOL File]
34218-80-9.mol | [Molecular Weight]
274.29 |
| Hazard Information | Back Directory | [Uses]
2’-O-Methyl-4-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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