ChemicalBook--->CAS DataBase List--->3436-44-0

3436-44-0

3436-44-0 Structure

3436-44-0 Structure
IdentificationBack Directory
[Name]

1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
[CAS]

3436-44-0
[Synonyms]

10:0 PC
PC(10:0/10:0)
1,2-Didecanoyl PC
Didecanoyllecithin
LecithinL-a-Dicaproyl
L-A-DICAPRYL LECITHIN
Dicaprylphosphatidylcholine
COATSOME MC-1010 (DDPC, DCPC)
Didecanoylphosphatidylcholine
L-Didecanoylphosphatidylcholine
L-α-Phosphatidylcholine, didecanoyl
L-alpha-Didecanoylphosphatidylcholine
Didecanoyl-L-α-glycerophosphorylcholine
L-ALPHA-PHOSPHATIDYLCHOLINE, DIDECANOYL
1 2-DIDECANOYL-SN-GLYCERO-3-PHOSPHO- &
3-SN-PHOSPHATIDYLCHOLINE, 1,2-DIDECANOYL
1,2-DICAPRYL-SN-GLYCERO-3-PHOSPHOCHOLINE
1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
1,2-DICAPRINOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
L-A-PHOSPHATIDYLCHOLINE, DIDECANOYL*(C10 :0)
1,2-DECANOYL-SN-GLYCERO-3-PHOSPHATIDYLCHOLINE
[O-(1-O,2-O-Didecanoyl-L-glycero-3-phospho)choline]anion
[O-[1-O,2-O-Didecanoyl-L-glycero-3-phospho]choline]anion
2,3-dicapryloxypropyl 2-(trimethylammonio)ethyl phosphate
2,3-di(decanoyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate
(R)-2,3-Bis(decanoyloxy)propyl (2-(trimethylammonio)ethyl) phosphate
(7R)-4-Hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxodecyl)oxy]-3,5,9-trioxa-4-phosphanonadecan-1-aminium 4-oxide, inner salt
1,2-Dicaprinoyl-sn-glycero-3-phosphocholine, 3-sn-Phosphatidylcholine, 1,2-didecanoyl, L-α-Phosphatidylcholine, didecanoyl
1,2-Didecanoyl-sn-glycero-3-phosphocholine,1,2-Dicaprinoyl-sn-glycero-3-phosphocholine, 3-sn-Phosphatidylcholine, 1,2-didecanoyl, L-α-Phosphatidylcholine, didecanoyl
[Molecular Formula]

C28H56NO8P
[MDL Number]

MFCD00063538
[MOL File]

3436-44-0.mol
[Molecular Weight]

565.72
Chemical PropertiesBack Directory
[storage temp. ]

−20°C
[solubility ]

Ethanol: 30 mg/ml; DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol:PBS (pH 7.2)(1:1): 0.5 mg/ml
[form ]

powder
[color ]

White to off-white
[BRN ]

3757665
Hazard InformationBack Directory
[Definition]

ChEBI: A 1,2-diacyl-sn-glycero-3-phosphocholine in which the acyl groups at positions 1 and 2 are specified as capryl (decanoyl).
[Description]

Phosphatidylcholine species are a common class of phospholipids that comprise the mammalian cell membrane. 1,2-Didecanoyl PC (DPC) is a synthetic, less hydrophobic phospholipid that has been found to be useful for enhancing the absorption of peptide drugs and hormones such as insulin. Thus, the bioavailability of intranasally applied human growth hormone is enhanced when coadministered with the absorption enhancer DPC.
[Uses]

1,2-Didecanoyl PC is a synthetic phospholipid.
[References]

[1] CARINA AGERHOLM. Epithelial transport and bioavailability of intranasally administered human growth hormone formulated with the absorption enhancers didecanoyl-L-α-phosphatidylcholine and α-cyclodextrin in rabbits[J]. Journal of pharmaceutical sciences, 1994, 83 12: 1706-1711. DOI: 10.1002/jps.2600831212
Safety DataBack Directory
[Symbol(GHS) ]


GHS06,GHS08
[Signal word ]

Danger
[Hazard statements ]

H302-H315-H319-H331-H336-H351-H361d-H372
[Precautionary statements ]

P202-P301+P312-P302+P352-P304+P340+P311-P305+P351+P338-P308+P313
[WGK Germany ]

3
[F ]

10-21
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