ChemicalBook--->CAS DataBase List--->344402-35-3

344402-35-3

344402-35-3 Structure

344402-35-3 Structure
IdentificationBack Directory
[Name]

5-Carboxy-X-rhodamine N-succinimidyl ester
[CAS]

344402-35-3
[Synonyms]

5-ROX NHS ester
ROX NHS ester, 5-isomer
Spiro[isobenzofuran-1(3H),9'-[1H,5H,9H,11H,15H]xantheno[2,3,4-ij:5,6,7-i'j']diquinolizine]-5-carboxylic acid, 2',3',6',7',12',13',16',17'-octahydro-3-oxo-, 2,5-dioxo-1-pyrrolidinyl ester
[Molecular Formula]

C37H33N3O7
[MDL Number]

MFCD00269773
[MOL File]

344402-35-3.mol
[Molecular Weight]

631.67
Chemical PropertiesBack Directory
[density ]

1.55±0.1 g/cm3(Predicted)
[solubility ]

Soluble in DMF, DMSO
[pka]

5.17±0.20(Predicted)
[Appearance]

dark red solid
Hazard InformationBack Directory
[Description]

ROX NHS ester, 5-isomer is a ROX dye linker that is commonly used for oligonucleotide labeling. The NHS ester can react specifically and efficiently with primary amines such as the side chain of lysine residue or aminosilane-coated surfaces at neutral or slight basic conditions to form a covalent bond.
[Uses]

5-Carboxy-X-rhodamine N-succinimidyl ester is a nucleotide labeling reagent.
[Chemical Reactivity]

Primary amines
[Abs/Em Maxima]

570/591 nm
[Fluoresene quantum yield]

1
[Extinction Coefficient]

93000
[CF260]

0.62
[CF280]

0.49
[Spectrally Similar Dyes]

Alexa Fluor® 568, TAMRA, CF™ 568
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