ChemicalBook--->CAS DataBase List--->344423-98-9

344423-98-9

344423-98-9 Structure

344423-98-9 Structure
IdentificationBack Directory
[Name]

Atorvastatin hemicalcium trihydrate
[CAS]

344423-98-9
[Synonyms]

liptonorm)
Atorvastatin Calcium –IP/USP
atorvastatin calcium hydrate
Atorvastatin Calcium (100 mg)
Atorvastatin calcium trihydrate CRS
Atorvastatin hemicalcium trihydrate
Atorvastatin CalciuM Trihydrate (EP)
Atorvastatin Hemicalcium Sesquihydrate
Atorvastatin calcium trihydrate (CI981
Atorvastatin Calcium Salt Trihydrate>
Atorvastatin calcium trihydrate (Y0001327)
Atorvastatin hemicalcium salt sesquihydrate
Calcium (3R,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate trihydrate
bis((3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phen ylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-di hydroxyheptanoic acid) calcium trihydrate
1H-Pyrrole-1-heptanoicacid, 2-(4-fluorophenyl)-b,d-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-,calcium salt, hydrate (2:1:3), (bR,dR)-
1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, calcium salt (2:1), trihydrate, (βR,δR)-
[Molecular Formula]

2(C33H34FN2O5).Ca.3(H2O)
[MDL Number]

MFCD09752074
[MOL File]

344423-98-9.mol
[Molecular Weight]

1209.39
Chemical PropertiesBack Directory
[Appearance]

White or almost white powder.
[storage temp. ]

Sealed in dry,Room Temperature
[solubility ]

Very slightly soluble in water, slightly soluble in ethanol (96 per cent), practically insoluble in methylene chloride.
[form ]

neat
[color ]

White to Almost white
[Optical Rotation]

[α]/D -9.0 to -5.0°, c =0.5 in DMSO
[Merck ]

14,864
[Uses]

HMG Co-A reductase inhibitor; lipid-regulating drug.
[CAS DataBase Reference]

344423-98-9
Hazard InformationBack Directory
[Chemical Properties]

White or almost white powder.
[Definition]

ChEBI: A hydrate that is the trihydrate form of atorvastatin calcium.
[Biological Activity]

Atorvastatin calcium salt trihydrate is a specific inhibitor of β-Hydroxy β-methylglutaryl-CoA (HMG-CoA) reductase. HMG-CoA reductase is the enzyme th at catalyzes the conversion of HMG-CoA to mevalonatean early step in cholesterol biosynthesis. Atorvastatin is used in the treatment of hypercholesterolemia.
Safety DataBack Directory
[Symbol(GHS) ]

Health Hazard (GHS08)
GHS08
[Signal word ]

Danger
[Hazard statements ]

H351-H360D
[Precautionary statements ]

P201-P202-P280-P308+P313-P405-P501
[Hazard Codes ]

T
[Risk Statements ]

61-36
[Safety Statements ]

53-26-45
[WGK Germany ]

3
[HS Code ]

2933995300
Spectrum DetailBack Directory
[Spectrum Detail]

Atorvastatin hemicalcium trihydrate(344423-98-9)1HNMR
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